6KYR
Crystal structure of DCLK1 mutant (P675L) Autoinhibited Kinase Domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Serine/threonine-protein kinase DCLK1 | polymer | 328 | 36634.9 | 2 | UniProt (O15075) Pfam (PF00069) In PDB | Homo sapiens (Human) | Doublecortin domain-containing protein 3A,Doublecortin-like and CAM kinase-like 1,Doublecortin-like kinase 1 |
| 2 | A, B | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 3 | Chemie (BME) | |||
| 3 | water | water | 18.0 | 382 | Chemie (HOH) |
Sequence modifications
A, B: 379 - 704 (UniProt: O15075)
| PDB | External Database | Details |
|---|---|---|
| Gly 377 | - | expression tag |
| Ser 378 | - | expression tag |
| Leu 675 | Pro 675 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 73269.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 234.4 | |
| All* | Total formula weight | 73504.1 |
