6JF0
Covalent labeling of hPPARg-LBD by turn-on fluorescent probe mediated by conjugate addition and cyclization
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Peroxisome proliferator-activated receptor gamma | polymer | 276 | 31449.5 | 2 | UniProt (P37231) Pfam (PF00104) In PDB | Homo sapiens (Human) | PPAR-gamma,Nuclear receptor subfamily 1 group C member 3 |
| 2 | A | methyl (2~{S})-3-[4-[3-(4-methoxy-2-oxidanyl-phenyl)prop-2-ynoyloxy]phenyl]-2-[[2-(phenylcarbonyl)phenyl]amino]propanoate | non-polymer | 549.6 | 1 | Chemie (EB6) | |||
| 3 | B | 7-methoxychromen-2-one | non-polymer | 176.2 | 1 | Chemie (EBF) | |||
| 4 | water | water | 18.0 | 12 | Chemie (HOH) |
Sequence modifications
A, B: 204 - 477 (UniProt: P37231)
| PDB | External Database | Details |
|---|---|---|
| Gly 202 | - | expression tag |
| Ala 203 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 62899.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 725.7 | |
| All* | Total formula weight | 63624.8 |
