6J7R

Crystal structure of toxin TglT (unusual type guanylyltransferase-like toxin, Rv1045) mutant S78A co-expressed with TakA from Mycobacterium tuberculosis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	guanylyltransferase-like toxin	polymer	313	34185.0	1	UniProt (P96356) Pfam (PF08843) In PDB	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
2	A	MAGNESIUM ION	non-polymer		24.3	20	Chemie (MG)
3		water	water		18.0	33	Chemie (HOH)

Sequence modifications

A: 1 - 293 (UniProt: P96356)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Ala 78	Ser 78	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	34185.0
Non-Polymers*	Number of molecules	20
	Total formula weight	486.1
All*	Total formula weight	34671.1

*Water molecules are not included.