6I4V

Alpha-1-antitrypsin Queen's (K154N) variant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Alpha-1-antitrypsin	polymer	404	45580.6	1	UniProt (P01009) Pfam (PF00079) In PDB	Homo sapiens (Human)	Alpha-1 protease inhibitor,Alpha-1-antiproteinase,Serpin A1
2	A	GLYCINE	non-polymer		75.1	2	Chemie (GLY)
3	A	3-trimethylsilylpropane-1-sulfonic acid	non-polymer		196.3	1	Chemie (H3B)
4		water	water		18.0	195	Chemie (HOH)

Sequence modifications

A: 2 - 394 (UniProt: P01009)

PDB	External Database	Details
Met -9	-	initiating methionine
Arg -8	-	expression tag
Gly -7	-	expression tag
Ser -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Thr 1	-	expression tag
Asn 154	Lys 178	engineered mutation
Ser 232	Cys 256	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	45580.6
Non-Polymers*	Number of molecules	3
	Total formula weight	346.5
All*	Total formula weight	45927.1

*Water molecules are not included.