6I49
Structure of P. aeruginosa LpxC with compound 17a: (2R)-N-Hydroxy-2-methyl-2-(methylsulfonyl)-4(6((4(morpholinomethyl)phenyl)ethynyl)-3-oxo-1H-pyrrolo[1,2-c]imidazol-2(3H)yl)butanamide
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | AAA, BBB | UDP-3-O-acyl-N-acetylglucosamine deacetylase | polymer | 299 | 33146.6 | 2 | UniProt (B7UZI4) Pfam (PF03331) In PDB | Pseudomonas aeruginosa LESB58 | UDP-3-O-acyl-GlcNAc deacetylase,UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase |
| 2 | AAA, BBB | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | AAA, BBB | (2~{R})-2-methyl-2-methylsulfonyl-4-[6-[2-[4-(morpholin-4-ylmethyl)phenyl]ethynyl]-3-oxidanylidene-1~{H}-pyrrolo[1,2-c]imidazol-2-yl]-~{N}-oxidanyl-butanamide | non-polymer | 514.6 | 2 | Chemie (H2Z) | |||
| 4 | water | water | 18.0 | 168 | Chemie (HOH) |
Sequence modifications
AAA, BBB: 1 - 299 (UniProt: B7UZI4)
| PDB | External Database | Details |
|---|---|---|
| Ser 40 | Cys 40 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 66293.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1160.0 | |
| All* | Total formula weight | 67453.2 |
