6HTF
Crystal structure of human Btk SH2 domain bound to rF10 repebody
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Tyrosine-protein kinase BTK | polymer | 117 | 13248.8 | 1 | UniProt (Q06187) Pfam (PF00017) In PDB | Homo sapiens (Human) | Agammaglobulinemia tyrosine kinase,ATK,B-cell progenitor kinase,BPK,Bruton tyrosine kinase |
2 | B | rF10 repebody | polymer | 274 | 31097.3 | 1 | synthetic construct | ||
3 | water | water | 18.0 | 126 | Chemie (HOH) |
Sequence modifications
A: 271 - 383 (UniProt: Q06187)
PDB | External Database | Details |
---|---|---|
Gly 267 | - | expression tag |
Ala 268 | - | expression tag |
Met 269 | - | expression tag |
Gly 270 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 44346.1 | |
All* | Total formula weight | 44346.1 |