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6HL0

Crystal Structure of Farnesoid X receptor (FXR) with bound NCoA-2 peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ABile acid receptorpolymer23227159.21UniProt (Q96RI1)
Pfam (PF00104)
In PDB
Homo sapiens (Human)Farnesoid X-activated receptor,Farnesol receptor HRR-1,Nuclear receptor subfamily 1 group H member 4,Retinoid X receptor-interacting protein 14,RXR-interacting protein 14
2BNCoA-2 peptide (Nuclear receptor coactivator 2), LYS-GLU-ASN-ALA-LEU-LEU-ARG-TYR-LEU-LEU-ASP-LYS-ASPpolymer131593.81Homo sapiens
3waterwater18.0140Chemie (HOH)
Sequence modifications
A: 244 - 472 (UniProt: Q96RI1)
PDBExternal DatabaseDetails
Ser 241-expression tag
His 242-expression tag
Met 243-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight28753.1
All*Total formula weight28753.1
*Water molecules are not included.

219869

PDB entries from 2024-05-15

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