6HL0
Crystal Structure of Farnesoid X receptor (FXR) with bound NCoA-2 peptide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Bile acid receptor | polymer | 232 | 27159.2 | 1 | UniProt (Q96RI1) Pfam (PF00104) In PDB | Homo sapiens (Human) | Farnesoid X-activated receptor,Farnesol receptor HRR-1,Nuclear receptor subfamily 1 group H member 4,Retinoid X receptor-interacting protein 14,RXR-interacting protein 14 |
2 | B | NCoA-2 peptide (Nuclear receptor coactivator 2), LYS-GLU-ASN-ALA-LEU-LEU-ARG-TYR-LEU-LEU-ASP-LYS-ASP | polymer | 13 | 1593.8 | 1 | Homo sapiens | ||
3 | water | water | 18.0 | 140 | Chemie (HOH) |
Sequence modifications
A: 244 - 472 (UniProt: Q96RI1)
PDB | External Database | Details |
---|---|---|
Ser 241 | - | expression tag |
His 242 | - | expression tag |
Met 243 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 28753.1 | |
All* | Total formula weight | 28753.1 |