6HFB

Outward-facing conformation of a multidrug resistance MATE family transporter of the MOP superfamily.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Uncharacterized protein	polymer	485	52256.4	4	UniProt (Q8U2X0) Pfam (PF01554) In PDB	Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
2	A, B, C, D	CESIUM ION	non-polymer		132.9	12	Chemie (CS)

Sequence modifications

A, B, C, D: 1 - 461 (UniProt: Q8U2X0)

PDB	External Database	Details
Thr 298	Ala 298	engineered mutation
Arg 462	-	expression tag
Asn 463	-	expression tag
Ser 464	-	expression tag
Glu 465	-	expression tag
Asn 466	-	expression tag
Leu 467	-	expression tag
Tyr 468	-	expression tag
Phe 469	-	expression tag
Gln 470	-	expression tag
Gly 471	-	expression tag
Gly 472	-	expression tag
Arg 473	-	expression tag
Gly 474	-	expression tag
Ser 475	-	expression tag
His 476	-	expression tag
His 477	-	expression tag
His 478	-	expression tag
His 479	-	expression tag
His 480	-	expression tag
His 481	-	expression tag
His 482	-	expression tag
His 483	-	expression tag
His 484	-	expression tag
His 485	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	209025.5
Non-Polymers*	Number of molecules	12
	Total formula weight	1594.9
All*	Total formula weight	210620.4

*Water molecules are not included.