6HCS

Crystal structure of CaM-peptide complex containing AzF at position 108

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G	Calmodulin-1	polymer	167	19014.9	4	UniProt (P0DP23) Pfam (PF13499) In PDB	Homo sapiens (Human)
2	B, D, F, H	Calcium/calmodulin-dependent protein kinase type II subunit beta	polymer	25	2886.5	4	UniProt (P08413) In PDB	Rattus norvegicus	CaMK-II subunit beta
3	A, C, E, G	CALCIUM ION	non-polymer		40.1	16	Chemie (CA)
4		water	water		18.0	243	Chemie (HOH)

Sequence modifications

A, C, E, G: 0 - 148 (UniProt: P0DP23)

PDB	External Database	Details
4ii 108	Val 109	engineered mutation
Leu 149	-	expression tag
Glu 150	-	expression tag
Gly 151	-	expression tag
Thr 152	-	expression tag
Gly 153	-	expression tag
Leu 154	-	expression tag
Glu 155	-	expression tag
Val 156	-	expression tag
Leu 157	-	expression tag
Phe 158	-	expression tag
Gln 159	-	expression tag
Gly 160	-	expression tag
His 161	-	expression tag
His 162	-	expression tag
His 163	-	expression tag
His 164	-	expression tag
His 165	-	expression tag
His 166	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	87605.6
Non-Polymers*	Number of molecules	16
	Total formula weight	641.2
All*	Total formula weight	88246.9

*Water molecules are not included.