6HBU
Cryo-EM structure of the ABCG2 E211Q mutant bound to ATP and Magnesium
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | ATP-binding cassette sub-family G member 2 | polymer | 655 | 72384.9 | 2 | UniProt (Q9UNQ0) Pfam (PF00005) Pfam (PF19055) Pfam (PF01061) In PDB | Homo sapiens (Human) | Breast cancer resistance protein,CDw338,Mitoxantrone resistance-associated protein,Placenta-specific ATP-binding cassette transporter,Urate exporter |
| 2 | A, B | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
| 3 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) |
Sequence modifications
A, B: 1 - 655 (UniProt: Q9UNQ0)
| PDB | External Database | Details |
|---|---|---|
| Gln 211 | Glu 211 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 144769.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1063.0 | |
| All* | Total formula weight | 145832.7 |
