6GQD
Structure of human galactose-1-phosphate uridylyltransferase (GALT), with crystallization epitope mutations A21Y:A22T:T23P:R25L
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Galactose-1-phosphate uridylyltransferase | polymer | 380 | 43580.2 | 1 | UniProt (P07902) Pfam (PF01087) Pfam (PF02744) In PDB | Homo sapiens (Human) | Gal-1-P uridylyltransferase,UDP-glucose--hexose-1-phosphate uridylyltransferase |
| 2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | A | 5,6-DIHYDROURIDINE-5'-MONOPHOSPHATE | non-polymer | 326.2 | 1 | Chemie (H2U) | |||
| 5 | water | water | 18.0 | 449 | Chemie (HOH) |
Sequence modifications
A: 1 - 379 (UniProt: P07902)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| Tyr 21 | Ala 21 | conflict |
| Thr 22 | Ala 22 | conflict |
| Pro 23 | Thr 23 | conflict |
| Leu 25 | Arg 25 | conflict |
| Asp 314 | Asn 314 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 43580.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 515.7 | |
| All* | Total formula weight | 44096.0 |
