6GDZ
exendin-4 based dual GLP-1/glucagon receptor agonist
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Exendin-4 | polymer | 40 | 4142.6 | 1 | UniProt (P26349) Pfam (PF00123) In PDB | Heloderma suspectum | |
2 | A | (2~{S})-2-[[(4~{S})-4-(hexadecanoylamino)-5-oxidanyl-5-oxidanylidene-pentanoyl]amino]pentanedioic acid | non-polymer | 514.7 | 1 | Chemie (EVT) |
Sequence modifications
A: 1 - 39 (UniProt: P26349)
PDB | External Database | Details |
---|---|---|
Aib 2 | Gly 49 | conflict |
Gln 3 | Glu 50 | conflict |
Lys 14 | Met 61 | conflict |
Asp 15 | Glu 62 | conflict |
Gln 17 | Glu 64 | conflict |
Arg 18 | Ala 65 | conflict |
Ala 19 | Val 66 | conflict |
Lys 20 | Arg 67 | conflict |
Aib 27 | Lys 74 | conflict |
Ala 28 | Asn 75 | conflict |
Nh2 40 | - | amidation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 4142.6 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 514.7 | |
All* | Total formula weight | 4657.2 |