6F3G
IRAK4 IN COMPLEX WITH inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Interleukin-1 receptor-associated kinase 4 | polymer | 295 | 33395.6 | 1 | UniProt (Q9NWZ3) Pfam (PF07714) In PDB | Homo sapiens (Human) | IRAK-4,Renal carcinoma antigen NY-REN-64 |
| 2 | B | Interleukin-1 receptor-associated kinase 4 | polymer | 295 | 33315.7 | 1 | UniProt (Q9NWZ3) Pfam (PF07714) In PDB | Homo sapiens (Human) | IRAK-4,Renal carcinoma antigen NY-REN-64 |
| 3 | A, B | ~{N}4,~{N}4-dimethyl-~{N}1-(5-propan-2-ylpyrrolo[3,2-d]pyrimidin-4-yl)cyclohexane-1,4-diamine | non-polymer | 301.4 | 2 | Chemie (CJN) | |||
| 4 | B | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | water | water | 18.0 | 71 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 66711.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 698.9 | |
| All* | Total formula weight | 67410.2 |
