6EG1

Crystal structure of Dpr2 Ig1-Ig2 in complex with DIP-Theta Ig1-Ig3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Defective proboscis extension response 2, isoform F	polymer	231	25771.3	2	UniProt (Q59DZ4) Pfam (PF07686) In PDB	Drosophila melanogaster (Fruit fly)	Dpr2, Defective proboscis extension response 2,isoform G
2	B, D	Dpr-interacting protein theta	polymer	302	34110.2	2	UniProt (Q9VMN6) Pfam (PF07686) Pfam (PF13927) In PDB	Drosophila melanogaster (Fruit fly)	DIP-Theta, FI23919p1
3	E, I, J, K, N	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	5	In PDB GlyTouCan (G21290RB)
4	F, L	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		894.8	2	In PDB GlyTouCan (G42466VF)
5	G, M	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		732.7	2	In PDB GlyTouCan (G32152BH)
6	H	alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		367.3	1	In PDB GlyTouCan (G86851RC)
7	O	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
8	C	CITRATE ANION	non-polymer		189.1	2	Chemie (FLC)
9	C, D	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	2	Chemie (PEG)
10	C	(R,R)-2,3-BUTANEDIOL	non-polymer		90.1	2	Chemie (BU3)
11	D	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
12		water	water		18.0	54	Chemie (HOH)

Sequence modifications

A, C: 103 - 323 (UniProt: Q59DZ4)

PDB	External Database	Details
Gly 101	-	expression tag
Ser 102	-	expression tag
His 324	-	expression tag
His 325	-	expression tag
His 326	-	expression tag
His 327	-	expression tag
His 328	-	expression tag
His 329	-	expression tag
His 330	-	expression tag
His 331	-	expression tag

B, D: 128 - 423 (UniProt: Q9VMN6)

PDB	External Database	Details
His 424	-	expression tag
His 425	-	expression tag
His 426	-	expression tag
His 427	-	expression tag
His 428	-	expression tag
His 429	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	119763.0
Branched	Number of molecules	11
	Total formula weight	6899.5
Non-Polymers*	Number of molecules	7
	Total formula weight	991.9
All*	Total formula weight	127654.3

*Water molecules are not included.