6EC0
Crystal structure of the wild-type heterocomplex between coil 1B domains of human intermediate filament proteins keratin 1 (KRT1) and keratin 10 (KRT10)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Keratin 1 | polymer | 107 | 12764.2 | 1 | UniProt (H6VRG1) Pfam (PF00038) In PDB | Homo sapiens (Human) | |
2 | B | Keratin, type I cytoskeletal 10 | polymer | 104 | 12121.5 | 1 | UniProt (P13645) Pfam (PF00038) In PDB | Homo sapiens (Human) | Cytokeratin-10,CK-10,Keratin-10,K10 |
3 | A, B | CADMIUM ION | non-polymer | 112.4 | 4 | Chemie (CD) | |||
4 | A, B | COBALT (II) ION | non-polymer | 58.9 | 2 | Chemie (CO) | |||
5 | B | NICKEL (II) ION | non-polymer | 58.7 | 2 | Chemie (NI) | |||
6 | water | water | 18.0 | 35 | Chemie (HOH) |
Sequence modifications
A: 226 - 331 (UniProt: H6VRG1)
B: 195 - 296 (UniProt: P13645)
PDB | External Database | Details |
---|---|---|
Met 225 | - | initiating methionine |
PDB | External Database | Details |
---|---|---|
Gly 193 | - | expression tag |
Ser 194 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 24885.7 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 684.9 | |
All* | Total formula weight | 25570.6 |