6E3M

The N-terminal domain of PA endonuclease from the influenza H1N1 virus in complex with 6-(3-carboxyphenyl)-3-hydroxy-4-oxo-1,4-dihydropyridine-2-carboxylic acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Polymerase acidic protein	polymer	192	22468.7	1	UniProt (C3W5S0) In PDB	Influenza A virus	RNA-directed RNA polymerase subunit P2
2	A	MANGANESE (II) ION	non-polymer		54.9	2	Chemie (MN)
3	A	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
4	A	6-(3-carboxyphenyl)-3-hydroxy-4-oxo-1,4-dihydropyridine-2-carboxylic acid	non-polymer		275.2	1	Chemie (HOG)
5		water	water		18.0	25	Chemie (HOH)

Sequence modifications

A: 1 - 198 (UniProt: C3W5S0)

PDB	External Database	Details
Met -5	-	expression tag
Gly -4	-	expression tag
Ser -3	-	expression tag
Gly -2	-	expression tag
Met -1	-	expression tag
Ala 0	-	expression tag
Gly 52	His 52	conflict
-	Phe 53	deletion
-	Ile 54	deletion
-	Asp 55	deletion
-	Glu 56	deletion
-	Arg 57	deletion
-	Gly 58	deletion
-	Glu 59	deletion
-	Ser 60	deletion
-	Ile 61	deletion
-	Ile 62	deletion
-	Val 63	deletion
-	Glu 64	deletion

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	22468.7
Non-Polymers*	Number of molecules	4
	Total formula weight	447.2
All*	Total formula weight	22915.8

*Water molecules are not included.