6CD1

Crystal structure of Medicago truncatula serine hydroxymethyltransferase 3 (MtSHMT3), complexes with reaction intermediates

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, F	Serine hydroxymethyltransferase	polymer	455	49588.5	5	UniProt (G7ILW0) Pfam (PF00464) In PDB	Medicago truncatula (Barrel medic)
2	E, G, H	Serine hydroxymethyltransferase	polymer	455	49816.6	3	UniProt (G7ILW0) Pfam (PF00464) In PDB	Medicago truncatula (Barrel medic)
3	A, D	[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-SERINE	non-polymer		336.2	2	Chemie (PLS)
4	A, B, C, D, E...	1,2-ETHANEDIOL	non-polymer		62.1	8	Chemie (EDO)
5	B, F	N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE]	non-polymer		306.2	2	Chemie (PLG)
6	C, H	ACETATE ION	non-polymer		59.0	3	Chemie (ACT)
7	E, H	GLYCINE	non-polymer		75.1	2	Chemie (GLY)
8		water	water		18.0	2032	Chemie (HOH)

Sequence modifications

A, B, C, D, F: 82 - 533 (UniProt: G7ILW0)

PDB	External Database	Details
Ser 79	-	expression tag
Asn 80	-	expression tag
Ala 81	-	expression tag

E, G, H: 82 - 533 (UniProt: G7ILW0)

PDB	External Database	Details
Ser 79	-	expression tag
Asn 80	-	expression tag
Ala 81	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	397392.1
Non-Polymers*	Number of molecules	17
	Total formula weight	2108.7
All*	Total formula weight	399500.8

*Water molecules are not included.