6C9U

Crystal structure of [KS3][AT3] didomain from module 3 of 6-deoxyerthronolide B synthase in complex with antibody fragment (Fab)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	6-deoxyerythronolide-B synthase EryA2, modules 3 and 4	polymer	941	99797.8	1	UniProt (Q03132) Pfam (PF08990) Pfam (PF00109) Pfam (PF02801) Pfam (PF16197) Pfam (PF00698) In PDB	Saccharopolyspora erythraea (Streptomyces erythraeus)	DEBS 2,6-deoxyerythronolide B synthase II,Erythronolide synthase,ORF B
2	L	Light chain of Fab 1B2	polymer	236	25715.8	1		Homo sapiens (Human)
3	H	Heavy chain of Fab 1B2	polymer	249	26447.6	1		Homo sapiens (Human)
4	A	POTASSIUM ION	non-polymer		39.1	1	Chemie (K)
5	A	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
6		water	water		18.0	680	Chemie (HOH)

Sequence modifications

A: 3 - 923 (UniProt: Q03132)

PDB	External Database	Details
Met 1	-	initiating methionine
Val 2	-	expression tag
Ala 439	Arg 438	conflict
Ser 481	Thr 480	conflict
Ser 924	-	expression tag
Ser 925	-	expression tag
Ser 926	-	expression tag
Val 927	-	expression tag
Asp 928	-	expression tag
Lys 929	-	expression tag
Leu 930	-	expression tag
Ala 931	-	expression tag
Ala 932	-	expression tag
Ala 933	-	expression tag
Leu 934	-	expression tag
Glu 935	-	expression tag
His 936	-	expression tag
His 937	-	expression tag
His 938	-	expression tag
His 939	-	expression tag
His 940	-	expression tag
His 941	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	151961.2
Non-Polymers*	Number of molecules	3
	Total formula weight	85.1
All*	Total formula weight	152046.3

*Water molecules are not included.