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6BTZ

Crystal structure of the PI3KC2alpha C2 domain in space group C121

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, DPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alphapolymer13114944.24UniProt (O00443)
Pfam (PF00168)
In PDB
Homo sapiens (Human)PtdIns-3-kinase C2 subunit alpha,Phosphoinositide 3-kinase-C2-alpha
2C, D, A, BSULFATE IONnon-polymer96.116Chemie (SO4)
3C, D, A, B1,4,7,10,13,16-HEXAOXACYCLOOCTADECANEnon-polymer264.36Chemie (O4B)
4C, A, BGLYCEROLnon-polymer92.17Chemie (GOL)
5waterwater18.0405Chemie (HOH)
Sequence modifications
A, B, C, D: 1559 - 1686 (UniProt: O00443)
PDBExternal DatabaseDetails
Ser -2-expression tag
Asn -1-expression tag
Ala 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight59776.7
Non-Polymers*Number of molecules29
Total formula weight3767.6
All*Total formula weight63544.3
*Water molecules are not included.

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PDB entries from 2024-05-15

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