6AYQ

Crystal structure of Campylobacter jejuni 5'-methylthioadenosine/S-adenosyl homocysteine nucleosidase (MTAN) complexed with methylthio-DADMe-Immucillin-A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase	polymer	238	26312.4	2	UniProt (A0A1E7P7U4) Pfam (PF01048) UniProt (by SIFTS) (Q0PC20) In PDB	Campylobacter jejuni
2	A, B	(3R,4S)-1-[(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)METHYL]-4-[(METHYLSULFANYL)METHYL]PYRROLIDIN-3-OL	non-polymer		293.4	2	Chemie (TDI)
3	B	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
4		water	water		18.0	471	Chemie (HOH)

Sequence modifications

A, B: 1 - 228 (UniProt: A0A1E7P7U4)

PDB	External Database	Details
Met -9	-	initiating methionine
Gly -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Ser -1	-	expression tag
Gly 0	-	expression tag
Asp 40	Asn 40	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	52624.9
Non-Polymers*	Number of molecules	3
	Total formula weight	678.9
All*	Total formula weight	53303.7

*Water molecules are not included.