6A73
Complex structure of CSN2 with IP6
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | COP9 signalosome complex subunit 2,Endolysin | polymer | 304 | 35315.4 | 2 | UniProt (P61201) UniProt (A0A097J809) Pfam (PF00959) UniProt (by SIFTS) (P00720) In PDB | Homo sapiens (Human) | Signalosome subunit 2,Alien homolog,JAB1-containing signalosome subunit 2,Thyroid receptor-interacting protein 15,TRIP-15,Lysis protein,Lysozyme,Muramidase |
2 | A, B | INOSITOL HEXAKISPHOSPHATE | non-polymer | 660.0 | 2 | Chemie (IHP) | |||
3 | A, B | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
4 | water | water | 18.0 | 171 | Chemie (HOH) |
Sequence modifications
A, B: 29 - 162 (UniProt: P61201)
A, B: 163 - 325 (UniProt: A0A097J809)
PDB | External Database | Details |
---|---|---|
Met 28 | - | initiating methionine |
PDB | External Database | Details |
---|---|---|
Thr 215 | Cys 54 | engineered mutation |
Ala 258 | Cys 97 | engineered mutation |
His 326 | - | expression tag |
His 327 | - | expression tag |
His 328 | - | expression tag |
His 329 | - | expression tag |
His 330 | - | expression tag |
His 331 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 70630.8 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1512.2 | |
All* | Total formula weight | 72143.0 |