5YFN
Human isocitrate dehydrogenase 1 bound with isocitrate
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Isocitrate dehydrogenase [NADP] cytoplasmic | polymer | 421 | 47604.2 | 2 | UniProt (O75874) Pfam (PF00180) In PDB | Homo sapiens (Human) | IDH,Cytosolic NADP-isocitrate dehydrogenase,IDP,NADP(+)-specific ICDH,Oxalosuccinate decarboxylase |
2 | A | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
3 | A | ISOCITRIC ACID | non-polymer | 192.1 | 2 | Chemie (ICT) | |||
4 | A, B | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
5 | water | water | 18.0 | 205 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 414 (UniProt: O75874)
PDB | External Database | Details |
---|---|---|
Asn -6 | - | expression tag |
Leu -5 | - | expression tag |
Tyr -4 | - | expression tag |
Phe -3 | - | expression tag |
Gln -2 | - | expression tag |
Ser -1 | - | expression tag |
Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 95208.5 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 511.1 | |
All* | Total formula weight | 95719.5 |