5YAK
The crystal structure of human IYD Thr239 mutant with ligand 3-Fluorotyrosine (F-Tyr)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Iodotyrosine deiodinase 1 | polymer | 264 | 30538.0 | 6 | UniProt (Q6PHW0) Pfam (PF00881) In PDB | Homo sapiens (Human) | IYD-1,Iodotyrosine dehalogenase 1 |
2 | A, B, C, D, E... | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 6 | Chemie (FMN) | |||
3 | A, B, C, D, E... | 3-FLUOROTYROSINE | non-polymer | 199.2 | 6 | Chemie (YOF) | |||
4 | water | water | 18.0 | 297 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 32 - 289 (UniProt: Q6PHW0)
PDB | External Database | Details |
---|---|---|
Ala 239 | Thr 239 | engineered mutation |
His 290 | - | expression tag |
His 291 | - | expression tag |
His 292 | - | expression tag |
His 293 | - | expression tag |
His 294 | - | expression tag |
His 295 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 183227.7 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 3933.1 | |
All* | Total formula weight | 187160.8 |