5XFS

Crystal structure of PE8-PPE15 in complex with EspG5 from M. tuberculosis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	PE family protein PE8	polymer	104	10271.4	1	UniProt (L7N667) Pfam (PF00934) In PDB	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
2	B	PPE family protein PPE15	polymer	202	20312.9	1	UniProt (P9WI31) Pfam (PF00823) In PDB	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	Mycobacterial perilipin-1,MPER1
3	C	ESX-5 secretion-associated protein EspG5	polymer	308	33529.7	1	UniProt (O53943) Pfam (PF14011) In PDB	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
4		water	water		18.0	27	Chemie (HOH)

Sequence modifications

A: 1 - 99 (UniProt: L7N667)

PDB	External Database	Details
Gly -4	-	expression tag
Pro -3	-	expression tag
Leu -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

B: 1 - 194 (UniProt: P9WI31)

PDB	External Database	Details
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
Met 0	-	expression tag

C: 1 - 300 (UniProt: O53943)

PDB	External Database	Details
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
Met 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	64114.0
All*	Total formula weight	64114.0

*Water molecules are not included.