5W9S

Zinc finger of human CXXC5 in complex with CpG DNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	CpG DNA fragment	polymer	12	3663.4	2		synthetic construct
2	C	CXXC-type zinc finger protein 5	polymer	71	8335.8	1	UniProt (Q7LFL8) Pfam (PF02008) In PDB	Homo sapiens (Human)	CF5,Putative MAPK-activating protein PM08,Putative NF-kappa-B-activating protein 102,Retinoid-inducible nuclear factor,RINF
3	C	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
4	C	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
5	C	UNKNOWN ATOM OR ION	non-polymer			1	Chemie (UNX)
6		water	water		18.0	12	Chemie (HOH)

Sequence modifications

C: 254 - 306 (UniProt: Q7LFL8)

PDB	External Database	Details
Met 236	-	initiating methionine
His 237	-	expression tag
His 238	-	expression tag
His 239	-	expression tag
His 240	-	expression tag
His 241	-	expression tag
His 242	-	expression tag
Ser 243	-	expression tag
Ser 244	-	expression tag
Gly 245	-	expression tag
Arg 246	-	expression tag
Glu 247	-	expression tag
Asn 248	-	expression tag
Leu 249	-	expression tag
Tyr 250	-	expression tag
Phe 251	-	expression tag
Gln 252	-	expression tag
Gly 253	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	15662.6
Non-Polymers*	Number of molecules	4
	Total formula weight	226.9
All*	Total formula weight	15889.5

*Water molecules are not included.