5TJ9
2.6 Angstrom Crystal Structure of S-adenosylhomocysteinase from Cryptosporidium parvum in Complex with Aristeromycin and NAD
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Adenosylhomocysteinase | polymer | 498 | 56200.7 | 4 | UniProt (Q5CPH1) Pfam (PF05221) Pfam (PF00670) In PDB | Cryptosporidium parvum (strain Iowa II) | |
| 2 | A, B, C, D | (1R,2S,3R,5R)-3-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)cyclopentane-1,2-diol | non-polymer | 265.3 | 4 | Chemie (7CY) | |||
| 3 | A, B, C, D | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
| 4 | D, A, B, C | SULFATE ION | non-polymer | 96.1 | 12 | Chemie (SO4) | |||
| 5 | A, B | HEXAETHYLENE GLYCOL | non-polymer | 282.3 | 2 | Chemie (P6G) | |||
| 6 | A, C | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 7 | D | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 8 | water | water | 18.0 | 381 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 495 (UniProt: Q5CPH1)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 224802.7 | |
| Non-Polymers* | Number of molecules | 27 |
| Total formula weight | 5934.7 | |
| All* | Total formula weight | 230737.4 |
