5T74
Human carboanhydrase F131C_C206S double mutant in complex with 14
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Carbonic anhydrase 2 | polymer | 260 | 29229.0 | 1 | UniProt (P00918) Pfam (PF00194) In PDB | Homo sapiens (Human) | Carbonate dehydratase II,Carbonic anhydrase C,CAC,Carbonic anhydrase II,CA-II |
2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
3 | A | 4-(HYDROXYMERCURY)BENZOIC ACID | non-polymer | 338.7 | 1 | Chemie (HGB) | |||
4 | A | 2-[2,5-bis(oxidanylidene)pyrrol-1-yl]-~{N}-(4-sulfamoylphenyl)ethanamide | non-polymer | 309.3 | 1 | Chemie (75Y) | |||
5 | A | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
6 | water | water | 18.0 | 369 | Chemie (HOH) |
Sequence modifications
A: 1 - 260 (UniProt: P00918)
PDB | External Database | Details |
---|---|---|
Cys 130 | Phe 130 | engineered mutation |
Ser 205 | Cys 205 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 29229.0 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 835.6 | |
All* | Total formula weight | 30064.5 |