5PB4
human factor VIIa in complex with 1-[[3-[5-hydroxy-3-methyl-4-(1H-pyrrolo[3,2-c]pyridin-2-yl)pyrazol-1-yl]phenyl]methyl]-3-phenylurea at 2.43A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Coagulation factor VII light chain | polymer | 64 | 6984.9 | 1 | UniProt (P08709) Pfam (PF14670) In PDB | Homo sapiens (Human) | Proconvertin,Serum prothrombin conversion accelerator,SPCA |
| 2 | C | Coagulation factor VII heavy chain | polymer | 254 | 28103.3 | 1 | UniProt (P08709) Pfam (PF00089) In PDB | Homo sapiens (Human) | Proconvertin,Serum prothrombin conversion accelerator,SPCA |
| 3 | A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | C | N-({3-[5-hydroxy-3-methyl-4-(1H-pyrrolo[3,2-c]pyridin-2-yl)-1H-pyrazol-1-yl]phenyl}methyl)-N'-phenylurea | non-polymer | 438.5 | 1 | Chemie (9RS) | |||
| 5 | C | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 6 | C | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 7 | C | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 8 | water | water | 18.0 | 209 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35088.2 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 829.7 | |
| All* | Total formula weight | 35917.9 |
