5NIU
Structure of human Programmed cell death 1 ligand 1 (PD-L1) with low molecular mass inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Programmed cell death 1 ligand 1 | polymer | 128 | 14678.8 | 4 | UniProt (Q9NZQ7) Pfam (PF07686) In PDB | Homo sapiens (Human) | Programmed death ligand 1,B7 homolog 1,B7-H1 |
2 | A, D | (2~{R})-2-[[2-[(3-cyanophenyl)methoxy]-4-[[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methyl-phenyl]methoxy]-5-methyl-phenyl]methylamino]-3-oxidanyl-propanoic acid | non-polymer | 594.7 | 2 | Chemie (8YZ) | |||
3 | A, C | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
4 | water | water | 18.0 | 318 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 18 - 134 (UniProt: Q9NZQ7)
PDB | External Database | Details |
---|---|---|
Ala 135 | - | expression tag |
Ala 136 | - | expression tag |
Ala 137 | - | expression tag |
Leu 138 | - | expression tag |
Glu 139 | - | expression tag |
His 140 | - | expression tag |
His 141 | - | expression tag |
His 142 | - | expression tag |
His 143 | - | expression tag |
His 144 | - | expression tag |
His 145 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 58715.0 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1313.4 | |
All* | Total formula weight | 60028.5 |