5MZE
Crystal structure of mouse MTH1 with 8-oxo-dGTP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | 7,8-dihydro-8-oxoguanine triphosphatase | polymer | 176 | 20101.7 | 4 | UniProt (P53368) Pfam (PF00293) In PDB | Mus musculus (House Mouse) | 2-hydroxy-dATP diphosphatase,8-oxo-dGTPase,Nucleoside diphosphate-linked moiety X motif 1,Nudix motif 1 |
2 | A, B, C | COPPER (II) ION | non-polymer | 63.5 | 4 | Chemie (CU) | |||
3 | A, D | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
4 | A, B, C, D | 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 4 | Chemie (8DG) | |||
5 | B | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
6 | water | water | 18.0 | 408 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 156 (UniProt: P53368)
PDB | External Database | Details |
---|---|---|
Met -19 | - | initiating methionine |
Gly -18 | - | expression tag |
Ser -17 | - | expression tag |
Ser -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
Ser -9 | - | expression tag |
Ser -8 | - | expression tag |
Gly -7 | - | expression tag |
Leu -6 | - | expression tag |
Val -5 | - | expression tag |
Pro -4 | - | expression tag |
Arg -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 80406.6 | |
Non-Polymers* | Number of molecules | 11 |
Total formula weight | 2651.2 | |
All* | Total formula weight | 83057.9 |