5LYY
Fragment-based inhibitors of Lipoprotein associated Phospholipase A2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Platelet-activating factor acetylhydrolase | polymer | 388 | 44203.1 | 1 | UniProt (Q13093) Pfam (PF03403) In PDB | Homo sapiens (Human) | PAF acetylhydrolase,1-alkyl-2-acetylglycerophosphocholine esterase,2-acetyl-1-alkylglycerophosphocholine esterase,Group-VIIA phospholipase A2,gVIIA-PLA2,LDL-associated phospholipase A2,LDL-PLA(2),PAF 2-acylhydrolase |
| 2 | A | 3-[2-(4-fluoranylphenoxy)ethyl]-1,3-diazaspiro[4.5]decane-2,4-dione | non-polymer | 306.3 | 1 | Chemie (7BJ) | |||
| 3 | water | water | 18.0 | 232 | Chemie (HOH) |
Sequence modifications
A: 46 - 428 (UniProt: Q13093)
| PDB | External Database | Details |
|---|---|---|
| His 429 | - | expression tag |
| His 430 | - | expression tag |
| His 431 | - | expression tag |
| His 432 | - | expression tag |
| His 433 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 44203.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 306.3 | |
| All* | Total formula weight | 44509.5 |
