5LY2
JMJD2A/ KDM4A COMPLEXED WITH NI(II), NOG AND Macrocyclic PEPTIDE Inhibitor CP2_R6Kme3 (13-mer)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Lysine-specific demethylase 4A | polymer | 381 | 44326.3 | 4 | UniProt (O75164) Pfam (PF02375) Pfam (PF02373) In PDB | Homo sapiens (Human) | JmjC domain-containing histone demethylation protein 3A,Jumonji domain-containing protein 2A |
2 | E, F, G, H | CP2_R6Kme3 | polymer | 14 | 1928.2 | 4 | synthetic construct | ||
3 | D, A, B, C | NICKEL (II) ION | non-polymer | 58.7 | 4 | Chemie (NI) | |||
4 | D, A, B, C | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
5 | D, A, B, C | N-OXALYLGLYCINE | non-polymer | 147.1 | 4 | Chemie (OGA) | |||
6 | A, B | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
7 | D, B, C | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
8 | water | water | 18.0 | 503 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 359 (UniProt: O75164)
PDB | External Database | Details |
---|---|---|
Met -21 | - | expression tag |
His -20 | - | expression tag |
His -19 | - | expression tag |
His -18 | - | expression tag |
His -17 | - | expression tag |
His -16 | - | expression tag |
His -15 | - | expression tag |
Ser -14 | - | expression tag |
Ser -13 | - | expression tag |
Gly -12 | - | expression tag |
Val -11 | - | expression tag |
Asp -10 | - | expression tag |
Leu -9 | - | expression tag |
Gly -8 | - | expression tag |
Thr -7 | - | expression tag |
Glu -6 | - | expression tag |
Asn -5 | - | expression tag |
Leu -4 | - | expression tag |
Tyr -3 | - | expression tag |
Phe -2 | - | expression tag |
Gln -1 | - | expression tag |
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 185017.8 | |
Non-Polymers* | Number of molecules | 22 |
Total formula weight | 1722.5 | |
All* | Total formula weight | 186740.3 |