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5KT4

Teranry complex of human DNA polymerase iota R96G inserting dCMPNPP opposite template G in the presence of Mg2+

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1TDNA (5'-D(*CP*TP*GP*GP*GP*GP*TP*CP*CP*T)-3')polymer103052.01synthetic construct
2PDNA (5'-D(P*AP*GP*GP*AP*CP*CP*C)-3')polymer72107.41synthetic construct
3ADNA polymerase iotapolymer44549617.91UniProt (Q9UNA4)
Pfam (PF00817)
Pfam (PF11799)
In PDB
Homo sapiens (Human)Eta2,RAD30 homolog B
4A2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidinenon-polymer466.21Chemie (0KX)
5AMAGNESIUM IONnon-polymer24.31Chemie (MG)
6waterwater18.022Chemie (HOH)
Sequence modifications
A: 1 - 445 (UniProt: Q9UNA4)
PDBExternal DatabaseDetails
Gly 96Arg 96engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight54777.3
Non-Polymers*Number of molecules2
Total formula weight490.5
All*Total formula weight55267.8
*Water molecules are not included.

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PDB entries from 2024-05-01

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