5KA5

HIV-1 gp41 variant V549E resistance mutation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Transmembrane glycoprotein gp41	polymer	91	10615.8	1	UniProt (P04578) Pfam (PF00517) In PDB	Human immunodeficiency virus type 1 (HIV-1)	Glycoprotein 41
2		water	water		18.0	32	Chemie (HOH)

Sequence modifications

A: 543 - 619 (UniProt: P04578)

PDB	External Database	Details
Met 542	-	initiating methionine
Glu 549	Val 549	engineered mutation

A: 625 - 661 (UniProt: P04578)

PDB	External Database	Details
Gly 620	-	linker
Gly 621	-	linker
Arg 622	-	linker
Gly 623	-	linker
Gly 624	-	linker
Gly 662	-	expression tag
Gly 663	-	expression tag
His 664	-	expression tag
His 665	-	expression tag
His 666	-	expression tag
His 667	-	expression tag
His 668	-	expression tag
His 669	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	10615.8
All*	Total formula weight	10615.8

*Water molecules are not included.