5JVH

The crystal structure large ribosomal subunit (50S) of Deinococcus radiodurans in complex with evernimicin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	X	23S ribosomal RNA	polymer	2880	933405.0	1	GenBank (1026245073)	Deinococcus radiodurans R1
2	Y	5S ribosomal RNA	polymer	123	39605.7	1	GenBank (11612676)	Deinococcus radiodurans R1
3	A	50S ribosomal protein L2	polymer	275	30107.8	1	UniProt (Q9RXJ9) Pfam (PF00181) Pfam (PF03947) In PDB	Deinococcus radiodurans R1
4	B	50S ribosomal protein L3	polymer	211	22477.2	1	UniProt (Q9RXK2) Pfam (PF00297) In PDB	Deinococcus radiodurans R1
5	C	50S ribosomal protein L4	polymer	205	22308.2	1	UniProt (Q9RXK1) Pfam (PF00573) In PDB	Deinococcus radiodurans R1
6	D	50S ribosomal protein L5	polymer	180	20379.9	1	UniProt (Q9RXJ0) Pfam (PF00281) Pfam (PF00673) In PDB	Deinococcus radiodurans R1
7	E	50S ribosomal protein L6	polymer	185	19613.6	1	UniProt (Q9RSL3) Pfam (PF00347) In PDB	Deinococcus radiodurans R1
8	G	50S ribosomal protein L13	polymer	174	19223.2	1	UniProt (Q9RXY1) Pfam (PF00572) In PDB	Deinococcus radiodurans R1
9	H	50S ribosomal protein L14	polymer	134	14256.5	1	UniProt (Q9RXJ2) Pfam (PF00238) In PDB	Deinococcus radiodurans R1
10	I	50S ribosomal protein L15	polymer	156	16894.2	1	UniProt (Q9RSK9) Pfam (PF00828) In PDB	Deinococcus radiodurans R1
11	J	50S ribosomal protein L16	polymer	141	16126.0	1	UniProt (Q9RXJ5) Pfam (PF00252) In PDB	Deinococcus radiodurans R1
12	K	50S ribosomal protein L17	polymer	116	12926.1	1	UniProt (Q9RSJ5) Pfam (PF01196) In PDB	Deinococcus radiodurans R1
13	L	50S ribosomal protein L18	polymer	114	12163.9	1	UniProt (Q9RSL2) Pfam (PF00861) In PDB	Deinococcus radiodurans R1
14	M	50S ribosomal protein L19	polymer	166	18347.8	1	UniProt (Q9RWB4) Pfam (PF01245) In PDB	Deinococcus radiodurans R1
15	N	50S ribosomal protein L20	polymer	118	13991.3	1	UniProt (Q9RSW7) Pfam (PF00453) In PDB	Deinococcus radiodurans R1
16	O	50S ribosomal protein L21	polymer	100	11165.7	1	UniProt (Q9RY64) Pfam (PF00829) In PDB	Deinococcus radiodurans R1
17	P	50S ribosomal protein L22	polymer	134	15190.9	1	UniProt (Q9RXJ7) Pfam (PF00237) In PDB	Deinococcus radiodurans R1
18	Q	50S ribosomal protein L23	polymer	95	10539.2	1	UniProt (Q9RXK0) Pfam (PF00276) In PDB	Deinococcus radiodurans R1
19	R	50S ribosomal protein L24	polymer	115	12384.4	1	UniProt (Q9RXJ1) Pfam (PF00467) Pfam (PF17136) In PDB	Deinococcus radiodurans R1
20	S	50S ribosomal protein L25	polymer	237	25415.4	1	UniProt (Q9RX88) Pfam (PF01386) Pfam (PF14693) In PDB	Deinococcus radiodurans R1	General stress protein CTC
21	T	50S ribosomal protein L27	polymer	91	9609.1	1	UniProt (Q9RY65) Pfam (PF01016) In PDB	Deinococcus radiodurans R1
22	U	50S ribosomal protein L28	polymer	81	8982.6	1	UniProt (Q9RRG8) Pfam (PF00830) In PDB	Deinococcus radiodurans R1
23	V	50S ribosomal protein L29	polymer	67	7775.0	1	UniProt (Q9RXJ4) Pfam (PF00831) In PDB	Deinococcus radiodurans R1
24	W	50S ribosomal protein L30	polymer	55	6079.2	1	UniProt (Q9RSL0) Pfam (PF00327) In PDB	Deinococcus radiodurans R1
25	Z	50S ribosomal protein L32	polymer	60	6810.0	1	UniProt (P49228) Pfam (PF01783) In PDB	Deinococcus radiodurans R1
26	1	50S ribosomal protein L33	polymer	54	6243.3	1	UniProt (Q9RSS4) Pfam (PF00471) In PDB	Deinococcus radiodurans R1
27	2	50S ribosomal protein L34	polymer	47	5626.6	1	UniProt (Q9RSH2) Pfam (PF00468) In PDB	Deinococcus radiodurans R1
28	3	50S ribosomal protein L35	polymer	66	7448.1	1	UniProt (Q9RSW6) Pfam (PF01632) In PDB	Deinococcus radiodurans R1
29	X	Evernimicin	non-polymer		1631.4	1	Chemie (6O1)
30	X, Y, K, M	MAGNESIUM ION	non-polymer		24.3	123	Chemie (MG)

Sequence modifications

X: 1 - 2880 (GenBank: 1026245073)

PDB	External Database	Details
U 1526	C 140011	conflict

Contents of the asymmetric unit

Polymers	Number of chains	28
	Total formula weight	1345095.9
Non-Polymers*	Number of molecules	124
	Total formula weight	4620.9
All*	Total formula weight	1349716.8

*Water molecules are not included.