5JJD

crystal structure of the ceramide transfer protein PH and START domain complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Collagen type IV alpha-3-binding protein	polymer	106	12345.6	1	UniProt (Q9Y5P4) Pfam (PF00169) In PDB	Homo sapiens (Human)	Ceramide transfer protein,hCERT,Goodpasture antigen-binding protein,GPBP,START domain-containing protein 11,StARD11,StAR-related lipid transfer protein 11
2	B	Collagen type IV alpha-3-binding protein	polymer	246	28037.9	1	UniProt (Q9Y5P4) Pfam (PF01852) In PDB	Homo sapiens (Human)	Ceramide transfer protein,hCERT,Goodpasture antigen-binding protein,GPBP,START domain-containing protein 11,StARD11,StAR-related lipid transfer protein 11
3	B	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	3	Chemie (PEG)
4	B	TRIETHYLENE GLYCOL	non-polymer		150.2	1	Chemie (PGE)
5		water	water		18.0	78	Chemie (HOH)

Sequence modifications

A: 20 - 122 (UniProt: Q9Y5P4)

PDB	External Database	Details
Gly 17	-	expression tag
Glu 18	-	expression tag
Phe 19	-	expression tag

B: 359 - 598 (UniProt: Q9Y5P4)

PDB	External Database	Details
Gly 353	-	expression tag
His 354	-	expression tag
Met 355	-	expression tag
Ala 356	-	expression tag
Met 357	-	expression tag
Glu 358	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	40383.5
Non-Polymers*	Number of molecules	4
	Total formula weight	468.5
All*	Total formula weight	40852.0

*Water molecules are not included.