5IVG

Crystal structure of Aspergillus terreus aristolochene synthase N299A complexed with farnesyl thiolodiphosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Aristolochene synthase	polymer	314	36178.4	4	UniProt (Q9UR08) Pfam (PF19086) In PDB	Aspergillus terreus	AS,Sesquiterpene cyclase
2	A, B, C, D	MAGNESIUM ION	non-polymer		24.3	12	Chemie (MG)
3	A, B, C, D	S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE	non-polymer		398.4	4	Chemie (FPS)
4	A, B, C	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
5		water	water		18.0	1372	Chemie (HOH)

Sequence modifications

A, B, C, D: 8 - 314 (UniProt: Q9UR08)

PDB	External Database	Details
Met 1	-	initiating methionine
His 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
Ala 299	Asn 305	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	144713.5
Non-Polymers*	Number of molecules	19
	Total formula weight	2161.5
All*	Total formula weight	146875.0

*Water molecules are not included.