5FYM
Crystal structure of JmjC domain of human histone demethylase UTY in complex with D-2-hydroxyglutarate
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | HISTONE DEMETHYLASE UTY | polymer | 478 | 55006.4 | 2 | UniProt (O14607) Pfam (PF02373) Pfam (PF21322) Pfam (PF21326) In PDB | HOMO SAPIENS (HUMAN) | UBIQUITOUSLY-TRANSCRIBED TPR PROTEIN ON THE Y CHROMOSOME, UBIQUITOUSLY-TRANSCRIBED Y CHROMOSOME TETRATRICOPEPTIDE REPEAT PROTEIN |
2 | A, B | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
3 | A, B | (2R)-2-hydroxypentanedioic acid | non-polymer | 148.1 | 2 | Chemie (2HG) | |||
4 | B, A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 28 | Chemie (EDO) | |||
5 | B, A | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
6 | water | water | 18.0 | 639 | Chemie (HOH) |
Sequence modifications
A, B: 799 - 1268 (UniProt: O14607)
PDB | External Database | Details |
---|---|---|
Met 798 | - | expression tag |
Ala 1269 | - | expression tag |
Glu 1270 | - | expression tag |
Asn 1271 | - | expression tag |
Leu 1272 | - | expression tag |
Tyr 1273 | - | expression tag |
Phe 1274 | - | expression tag |
Gln 1275 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 110012.8 | |
Non-Polymers* | Number of molecules | 34 |
Total formula weight | 2274.8 | |
All* | Total formula weight | 112287.6 |