5FSG
Structure of the hantavirus nucleoprotein provides insights into the mechanism of RNA encapsidation and a template for drug design
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | MALTOSE-BINDING PERIPLASMIC PROTEIN, HANTAVIRUS NUCLEOPROTEIN | polymer | 698 | 78120.3 | 1 | UniProt (P0AEX9) UniProt (P05133) Pfam (PF01547) Pfam (PF00846) In PDB | HANTAAN VIRUS | MBP, MMBP, MALTODEXTRIN-BINDING PROTEIN, NUCLEOCAPSID PROTEIN, PROTEIN N, HANTAVIRUS NUCLEOPROTEIN |
| 2 | B | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | branched | 666.6 | 1 | In PDB BIRD (PRD_900010) GlyTouCan (G87171PZ) | alpha-maltotetraose |
Sequence modifications
A: -372 - -14 (UniProt: P0AEX9)
A: 113 - 429 (UniProt: P05133)
| PDB | External Database | Details |
|---|---|---|
| Leu 430 | - | expression tag |
| Glu 431 | - | expression tag |
| His 432 | - | expression tag |
| His 433 | - | expression tag |
| His 434 | - | expression tag |
| His 435 | - | expression tag |
| His 436 | - | expression tag |
| His 437 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala -13 | - | linker |
| Ala -12 | - | linker |
| Leu -11 | - | linker |
| Ala -10 | - | linker |
| Ala -9 | - | linker |
| Gly -8 | - | linker |
| Ser -7 | - | linker |
| Ala -6 | - | linker |
| Gln -5 | - | linker |
| Thr -4 | - | linker |
| Asn -3 | - | linker |
| Ala -2 | - | linker |
| Ala -1 | - | linker |
| Ala 0 | - | linker |
| Asn 185 | Gln 185 | conflict |
| Asp 377 | Gly 377 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 78120.3 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 666.6 | |
| All* | Total formula weight | 78786.9 |
