5FPH

The GTPase domains of the immunity-related Irga6 dimerize in a parallel head-to-head fashion

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	INTERFERON-INDUCIBLE GTPASE 1	polymer	423	48972.0	7	UniProt (Q9QZ85) Pfam (PF05049) In PDB	MUS MUSCULUS (HOUSE MOUSE)	IMMUNITY-RELATED GTPASE 6
2	A, B, C, E, F...	PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER	non-polymer		522.2	6	Chemie (GNP)
3	G, A, B, C, D...	MAGNESIUM ION	non-polymer		24.3	13	Chemie (MG)
4	C, E	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	2	Chemie (TRS)
5		water	water		18.0	8	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G: 1 - 413 (UniProt: Q9QZ85)

PDB	External Database	Details
Gly -9	-	expression tag
Ser -8	-	expression tag
Pro -7	-	expression tag
Gly -6	-	expression tag
Ile -5	-	expression tag
Pro -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
Thr -1	-	expression tag
Thr 0	-	expression tag
Glu 31	Arg 31	engineered mutation
Glu 32	Lys 32	engineered mutation
Glu 176	Lys 176	engineered mutation
Glu 246	Lys 246	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	7
	Total formula weight	342804.3
Non-Polymers*	Number of molecules	21
	Total formula weight	3693.4
All*	Total formula weight	346497.8

*Water molecules are not included.