5FH6
Crystal structure of the fifth bromodomain of human PB1 in complex with compound 10
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Protein polybromo-1 | polymer | 124 | 14648.0 | 4 | UniProt (Q86U86) Pfam (PF00439) In PDB | Homo sapiens (Human) | hPB1,BRG1-associated factor 180,BAF180,Polybromo-1D |
| 2 | A, B, C, D | (3~{R})-3-(piperidin-1-ylmethyl)-2,3-dihydro-1~{H}-pyrrolo[1,2-a]quinazolin-5-one | non-polymer | 283.4 | 4 | Chemie (5XM) | |||
| 3 | water | water | 18.0 | 13 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 645 - 766 (UniProt: Q86U86)
| PDB | External Database | Details |
|---|---|---|
| Ser 643 | - | expression tag |
| Met 644 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 58592.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1133.5 | |
| All* | Total formula weight | 59725.5 |
