5F38

X-ray crystal structure of a thiolase from Escherichia coli at 1.8 A resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B	Acetyl-CoA acetyltransferase	polymer	393	40319.3	1	UniProt (P76461) Pfam (PF00108) Pfam (PF02803) In PDB	Escherichia coli K-12	Acetoacetyl-CoA thiolase
2	A	Acetyl-CoA acetyltransferase	polymer	394	40433.4	1	UniProt (P76461) Pfam (PF00108) Pfam (PF02803) In PDB	Escherichia coli K-12	Acetoacetyl-CoA thiolase
3	D	Acetyl-CoA acetyltransferase	polymer	394	40364.3	1	UniProt (P76461) Pfam (PF00108) Pfam (PF02803) In PDB	Escherichia coli K-12	Acetoacetyl-CoA thiolase
4	C	Acetyl-CoA acetyltransferase	polymer	395	40477.4	1	UniProt (P76461) Pfam (PF00108) Pfam (PF02803) In PDB	Escherichia coli K-12	Acetoacetyl-CoA thiolase
5	B	COENZYME A	non-polymer		767.5	1	Chemie (COZ)
6	D, B, C, A	1,2-ETHANEDIOL	non-polymer		62.1	31	Chemie (EDO)
7	C, D	[(3~{S})-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-4-[[3-oxidanylidene-3-(2-sulfanylethylamino)propyl]amino]butyl] phosphono hydrogen phosphate	non-polymer		438.3	2	Chemie (5UG)
8		water	water		18.0	1033	Chemie (HOH)

Sequence modifications

D: 1 - 392 (UniProt: P76461)

PDB	External Database	Details
Ala -1	-	expression tag
Ser 0	-	expression tag

C: 1 - 390 (UniProt: P76461)

PDB	External Database	Details
Ala -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	161594.4
Non-Polymers*	Number of molecules	34
	Total formula weight	3568.3
All*	Total formula weight	165162.7

*Water molecules are not included.