5EP6

The crystal structure of NAP1 in complex with TBK1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	5-azacytidine-induced protein 2	polymer	47	5631.5	2	UniProt (Q9H6S1) Pfam (PF12845) In PDB	Homo sapiens (Human)	NF-kappa-B-activating kinase-associated protein 1,Nak-associated protein 1,TILP
2	B, D	Serine/threonine-protein kinase TBK1	polymer	58	6324.2	2	UniProt (Q9UHD2) In PDB	Homo sapiens (Human)	NF-kappa-B-activating kinase,T2K,TANK-binding kinase 1
3	A, C, B, D	GLYCEROL	non-polymer		92.1	5	Chemie (GOL)
4		water	water		18.0	101	Chemie (HOH)

Sequence modifications

A, C: 215 - 255 (UniProt: Q9H6S1)

PDB	External Database	Details
Glu 256	-	expression tag
Asn 257	-	expression tag
Leu 258	-	expression tag
Tyr 259	-	expression tag
Phe 260	-	expression tag
Gln 261	-	expression tag

B, D: 677 - 729 (UniProt: Q9UHD2)

PDB	External Database	Details
Ser 672	-	expression tag
Gly 673	-	expression tag
Ser 674	-	expression tag
Gly 675	-	expression tag
Ser 676	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	23911.3
Non-Polymers*	Number of molecules	5
	Total formula weight	460.5
All*	Total formula weight	24371.8

*Water molecules are not included.