5E89
Crystal structure of Human galectin-3 CRD in complex with 3-fluophenyl-1,2,3-triazolyl thiodigalactoside inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Galectin-3 | polymer | 139 | 15758.1 | 1 | UniProt (P17931) Pfam (PF00337) In PDB | Homo sapiens (Human) | Gal-3,35 kDa lectin,Carbohydrate-binding protein 35,CBP 35,Galactose-specific lectin 3,Galactoside-binding protein,GALBP,IgE-binding protein,L-31,Laminin-binding protein,Lectin L-29,Mac-2 antigen |
| 2 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 3 | A | 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-beta-D-galactopyranoside | non-polymer | 648.6 | 1 | Chemie (TD2) | |||
| 4 | water | water | 18.0 | 162 | Chemie (HOH) |
Sequence modifications
A: 114 - 250 (UniProt: P17931)
| PDB | External Database | Details |
|---|---|---|
| Gly 112 | - | expression tag |
| Pro 113 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15758.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 684.1 | |
| All* | Total formula weight | 16442.2 |
