5DX8

Crystal structure of CARM1, sinefungin, and methylated PABP1 peptide (R455)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Histone-arginine methyltransferase CARM1	polymer	349	39623.1	4	UniProt (Q86X55) Pfam (PF06325) In PDB	Homo sapiens (Human)	Coactivator-associated arginine methyltransferase 1,Protein arginine N-methyltransferase 4
2	E, F, G, H	methylated PABP1 peptide	polymer	19	1937.3	4	UniProt (P11940) In PDB	Homo sapiens	Poly(A)-binding protein 1
3	A, B, C, D	SINEFUNGIN	non-polymer		381.4	4	Chemie (SFG)
4		water	water		18.0	349	Chemie (HOH)

Sequence modifications

A, B, C, D: 134 - 479 (UniProt: Q86X55)

PDB	External Database	Details
Ser 131	-	expression tag
Ile 132	-	expression tag
Ala 133	-	expression tag

E, F, G, H: 1 - 18 (UniProt: P11940)

PDB	External Database	Details
Nh2 19	-	amidation

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	166241.7
Non-Polymers*	Number of molecules	4
	Total formula weight	1525.5
All*	Total formula weight	167767.3

*Water molecules are not included.