5DMI
Structure of the extracellular domain of the CD40 in complex with CHI220 FAB
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Tumor necrosis factor receptor superfamily member 5 | polymer | 183 | 20084.4 | 1 | UniProt (P25942) Pfam (PF00020) In PDB | Homo sapiens (Human) | B-cell surface antigen CD40,Bp50,CD40L receptor,CDw40 |
| 2 | H | Chi220 Fab heavy chain | polymer | 223 | 23908.9 | 1 | Mus musculus Homo sapiens | ||
| 3 | L | Chi220 Fab light chain | polymer | 213 | 23361.8 | 1 | Mus musculus Homo sapiens | ||
| 4 | H, L | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
A: 23 - 193 (UniProt: P25942)
| PDB | External Database | Details |
|---|---|---|
| Asp 153 | Asn 153 | SEE REMARK 999 |
| Asp 180 | Asn 180 | SEE REMARK 999 |
| Asp 194 | - | expression tag |
| Pro 195 | - | expression tag |
| Gly 196 | - | expression tag |
| Gly 197 | - | expression tag |
| Gly 198 | - | expression tag |
| Gly 199 | - | expression tag |
| Gly 200 | - | expression tag |
| Arg 201 | - | expression tag |
| Leu 202 | - | expression tag |
| Val 203 | - | expression tag |
| Pro 204 | - | expression tag |
| Arg 205 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 67355.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 192.1 | |
| All* | Total formula weight | 67547.3 |
