5C7S

PRPP complexed with two Mn2+ in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Anthranilate phosphoribosyltransferase	polymer	379	38948.0	2	UniProt (P9WFX5) Pfam (PF02885) Pfam (PF00591) In PDB	Mycobacterium tuberculosis
2	A, B	MANGANESE (II) ION	non-polymer		54.9	4	Chemie (MN)
3	A, B	1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose	non-polymer		390.1	2	Chemie (PRP)
4		water	water		18.0	287	Chemie (HOH)

Sequence modifications

A, B: 2 - 370 (UniProt: P9WFX5)

PDB	External Database	Details
Met 0	-	expression tag
Val 1	-	expression tag
Leu 371	-	expression tag
Glu 372	-	expression tag
His 373	-	expression tag
His 374	-	expression tag
His 375	-	expression tag
His 376	-	expression tag
His 377	-	expression tag
His 378	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	77896.0
Non-Polymers*	Number of molecules	6
	Total formula weight	999.9
All*	Total formula weight	78895.9

*Water molecules are not included.