5AP9
Controlled lid-opening in Thermomyces lanuginosus lipase - a switch for activity and binding
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | LIPASE | polymer | 269 | 29322.5 | 2 | UniProt (O59952) Pfam (PF03893) Pfam (PF01764) In PDB | THERMOMYCES LANUGINOSUS | TRIACYLGLYCEROL LIPASE |
| 2 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 3 | A, B | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 5 | B | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 6 | water | water | 18.0 | 243 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 269 (UniProt: O59952)
| PDB | External Database | Details |
|---|---|---|
| Cys 86 | Ile 108 | engineered mutation |
| Cys 255 | Ile 277 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58644.9 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 607.6 | |
| All* | Total formula weight | 59252.5 |
