4ZYU

Human GAR transformylase in complex with GAR and N-{4-[4-(2-Amino-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-6-yl)-butyl]benzoyl}-L-glutamic acid (AGF50)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Trifunctional purine biosynthetic protein adenosine-3	polymer	210	22810.1	1	UniProt (P22102) Pfam (PF00551) In PDB	Homo sapiens (Human)
2	A	GLYCINAMIDE RIBONUCLEOTIDE	non-polymer		284.2	1	Chemie (GAR)
3	A	N-{4-[4-(2-amino-4-oxo-1,4-dihydrothieno[2,3-d]pyrimidin-6-yl)butyl]benzoyl}-L-glutamic acid	non-polymer		472.5	1	Chemie (3YA)
4		water	water		18.0	124	Chemie (HOH)

Sequence modifications

A: 808 - 1010 (UniProt: P22102)

PDB	External Database	Details
Met 807	-	initiating methionine
His 1011	-	expression tag
His 1012	-	expression tag
His 1013	-	expression tag
His 1014	-	expression tag
His 1015	-	expression tag
His 1016	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	22810.1
Non-Polymers*	Number of molecules	2
	Total formula weight	756.7
All*	Total formula weight	23566.8

*Water molecules are not included.