4YT6
Factor VIIa in complex with the inhibitor 4-{[(R)-[5-ethoxy-2-fluoro-3-(propan-2-yloxy)phenyl](4-phenyl-1H-imidazol-2-yl)methyl]amino}benzenecarboximidamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | H | Coagulation factor VII (heavy chain) | polymer | 254 | 28103.3 | 1 | UniProt (P08709) Pfam (PF00089) In PDB | Homo sapiens (Human) | Factor VIIa heavy chain, activated Factor VIIa heavy chain, Proconvertin, Serum prothrombin conversion accelerator, SPCA |
| 2 | L | Coagulation factor VII (light chain) | polymer | 57 | 6272.1 | 1 | UniProt (P08709) Pfam (PF14670) In PDB | Homo sapiens (Human) | Factor VIIa light chain, Proconvertin, Serum prothrombin conversion accelerator, SPCA |
| 3 | H | 4-[[(R)-(5-ethoxy-2-fluoranyl-3-propan-2-yloxy-phenyl)-(4-phenyl-1H-imidazol-2-yl)methyl]amino]benzenecarboximidamide | non-polymer | 487.6 | 1 | Chemie (4JY) | |||
| 4 | H | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | H | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 6 | H | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 7 | water | water | 18.0 | 301 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 34375.4 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1188.2 | |
| All* | Total formula weight | 35563.5 |
